Infection in Organs Transplant Cases

Acute

What are the Infections in Organ Transplant Recipients ?

These are infections that occurs in cases who have received either bone marrow or solid organ (Kidney, liver, lungs , heart etc) transplants. These infections are serious concerns as patients are in immunocompromised state due to ongoing medications and need timely intervention from an expert.

Symptoms

  • Fever
  • Cough
  • Shortness of breath
  • Decreased vision
  • Diarrhoea
  • Reduced graft function
  • Disseminated rashes
  • Generalised lymphadenopathy

Complications

  • Loss of graft
  • Septic shock
  • Bone marrow suppression

Causes

  • Bacterial: Various common or rare bacterial
  • Viral: fungal or parasitic infections like Pneumocystis pneumonia, CMV , Varicella etc

Risk Factors

  • Mismatched transplant
  • Multiple blood products infusion
  • Graft versus host disease
  • Intensive immunosuppressive drugs
  • CMV Disease

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